TYPHOID SHOT SIDE EFFECT PROFESSIONAL
Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. For this vaccine, the following should be considered: Allergies This is a decision you and your doctor will make. In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This product is available in the following dosage forms: This vaccine is to be given only by or under the supervision of your doctor or other health care professional.
Therefore, it is very important to avoid infected persons and food and water that may be infected, even if you have received the vaccine. Typhoid vaccine given by injection helps prevent typhoid fever, but does not provide 100% protection. Centers for Disease Control (CDC) currently recommend caution in the following areas of the world: If you are traveling to certain countries or remote, out-of-the-way areas, typhoid vaccine will help protect you from typhoid fever. However, it is a problem in parts of the world that do not have such systems. and other areas of the world that have good water and sewage (waste) systems. Some infected persons do not appear to be sick, but they can still spread the germ to others.
Typhoid may also be spread by close person-to-person contact with infected persons (such as occurs with persons living in the same household). It is spread most often through infected food or water.
TYPHOID SHOT SIDE EFFECT SKIN
A prior history of any other malignancy except basal or squamous cell skin cancers, strokes, diabetes, current heart disease or uncontrolled hypertension, peripheral vascular disease, liver disease, autoimmune and/or inflammatory diseases including rheumatoid arthritis and ulcerative colitis, and other medical conditions that would limit participation in the assessments (e.g.Typhoid fever is a serious disease that can cause death.Women who have been diagnosed with stage I-IIIA breast cancer will be recruited 1-10 years after the completion of all primary cancer treatment except for longer-term hormonal therapies (tamoxifen, aromatase inhibitors).Patients also complete cognitive tasks and a temperature sensitivity task at 3-4.5 hours post-injection. During visit 1 and 2, patients in both arms will have blood drawn periodically and complete sets of questionnaires that assess feelings, health behaviors, and personality. There is an initial screening visit where patients in both arms complete an audio-recorded interview that includes questions about changes in mood and emotion throughout their lives, body measurements, a finger stick to assess for anemia and diabetes markers. OUTLINE: Patients are randomized to 1 of 2 arms.ĪRM I: Patients receive inactive typhoid vaccine intramuscularly (IM) at visit 1 followed by placebo IM 30 days later at visit 2.ĪRM II: Patients receive placebo IM at visit 1 followed by inactive typhoid vaccine IM 30 days later at visit 2. To assess the ability of cardiorespiratory fitness to moderate age- and depression-related responses to typhoid vaccine. To determine the effects of age and depressive symptoms on inflammatory and behavioral responses to typhoid vaccine and placebo. To evaluate the relationships between cardiorespiratory fitness and inflammatory and behavioral responses (negative mood, fatigue, pain, and cognitive problems) to typhoid vaccine in breast cancer survivors. Condition or diseaseĬognitive Side Effects of Cancer Therapy Depression Recurrent Breast Carcinoma Stage IA Breast Cancer Stage IB Breast Cancer Stage IIA Breast Cancer Stage IIB Breast Cancer Stage IIIA Breast Cancerīiological: typhoid vaccine Other: Placebo Studying immune responses in patients with breast cancer who have undergone primary cancer treatment may help doctors learn whether physical fitness can protect the body from effects of immune system stress and whether it may be able to reduce health problems in patients with breast cancer. Immune responses may cause excess inflammation in the body and behavioral changes, such as depression, fatigue, pain, and problems with thinking and reasoning. A vaccine is a substance or group of substances meant to cause the immune system to respond to a tumor or to microorganisms such as bacteria or viruses.
TYPHOID SHOT SIDE EFFECT TRIAL
This randomized clinical trial uses an inactive typhoid vaccine to briefly stimulate an immune response in patients with stage I-IIIA breast cancer who received primary cancer treatment and studies whether patients' fitness levels affect how their bodies handle a challenge to their immune system. Why Should I Register and Submit Results?.
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